Cannabinoids are active compounds found in the cannabis plant, and there are a variety of them, with different effects and uses. Recent discoveries and synthetic modifications have led to new variants, including HHC, HHC-O, HHC-P, THCv, THCp, and muscimol. Here is a comparison of these substances:

HHC (hexahydrocannabinol)

• Extraction: HHC is a hydrogen-added analogue of THC and occurs naturally in very small amounts in the hemp plant. It can also be produced synthetically.
• Effects: HHC has similar psychotropic effects to THC, but is said to be slightly less intense.
• Legal Status: In some regions where THC is a controlled substance, HHC may still be legal due to its low natural presence and different structure.

HHC-O (acetate)

• Production: HHC-O is a chemically modified derivative of HHC to which acetic anhydride is added (acetylation).
• Effects: HHC-O is said to have a stronger effect than HHC because the acetate additive increases the bioavailability.
• Legal Status: The legal status of HHC-O is often unclear and may depend on local legislation on modified cannabinoids.

HHC-P (Phorol)

• Extraction: HHC-P is another synthetic variant of HHC with a modified side chain.
• Effects: HHC-P is reported to have stronger effects than HHC and THC.
• Legal Status: As with HHC-O, the legal status of HHC-P may vary.

THCv (tetrahydrocannabivarin)

• Extraction: THCv is a naturally occurring cannabinoid in certain cannabis strains.
• Effects: THCv can have appetite suppressant properties and is associated with a clear, energizing high.
• Legal status: THCv is regulated in many countries along with other THC compounds.

THCp (Tetrahydrocannabiphorol)

• Extraction: THCp is a natural component of some cannabis strains, but in very low concentrations.
• Effects: THCp binds very strongly to the CB1 and CB2 cannabinoid receptors and could potentially produce stronger effects than THC.
• Legal status: Because THCp is closely related to THC, it may be classified as a controlled substance in many regions.

Muscimol

• Extraction: Muscimol is a psychoactive isotoxal of the amino acid GABA and is extracted from the fly agaric species Amanita muscaria.
• Effects: Muscimol has sedative and hallucinogenic effects, but differs from the effects of cannabis cannabinoids.
• Legal Status: The legality of muscimol varies internationally and may be heavily regulated locally.

Please note that the legal framework for these substances can change quickly and it is important to be informed about the current legislation in your region. Research into these cannabinoids is also constantly evolving, so new findings on effects and safety can emerge.